£27.99
90 Softgels
Quantity:
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SesaMAX™ is a break through fat loss formula comprised of Sesamin Lignans with the added benefit of Omega-3 Fish Fats. SesaMAX™’s revolutionary, multi-faceted benefits increase fat oxidation (burning) while decreasing fat storage to get you lean and keep you lean! SesaMAX™ also turbo charges the effects of dieting by fueling ketosis when you cut carbohydrates. Axis Labs™ has gone above and beyond the competition by intergrading super potent EPA/DHA Fish Fats into SesaMAX™. Fish Fats has been scientifically proven to provide a rich source of essential fatty acids (EFA’s) and “good” fats. The synergistic combination of Sesamin Lignans and EFA’s can strongly improve healthy metabolic function, reduce oxidative stress, and improve cholesterol levels. Get a hard, healthy core by supplementing with SesaMAX™ now!
SesaMAX™ Highlights:
- Increases Fat Oxidation (burning)
- Decreases Fat Storage
- Increases Good Cholesterol (HDL)
- Decrease Bad Cholesterol (LDL)
- Fuels Ketosis (carb cutting)
- Effective Antioxidant
- Added benefits of Fish Fats
- Stimulant Free
- Easy to Swallow Liquid Softgels
What is Sesamin?
Sesamin is a lignan that is found in sesame seeds. A lignan is a molecule that combines with a receptor to activate that receptor, and create a response. The receptor and lignan will then perform a function in the body. Sesamin is a lignan for the Peroxisome Proliferator-ActivatorReceptor Alpha (PPARalpha). The receptor is found in muscle, liver, and heart tissue and is involved in the oxidation (burning) of fat. Activation of PPARalpha increases gene expression of the fatty acid oxidation (burning) enzymes and decreases gene expression of lipogenic (fat storing) enzymes. Sesamin has been shown to be a potent PPARalpha activator. The majority of fat oxidation occurs in skeletal muscle cells and the liver. PPARalpha activation by sesamin increases fat oxidation by increasing the expression of enzymes involved in the oxidation of fatty acids. SesaMAX™ can increase some types of enzymes that help shuttle fatty acids into the mitochondria of cells, where they are burned.
Decreased Fat Storage
SesaMAX™ is an amazing fat burning supplement for several reasons. First, Sesamin has been shown to decrease the lipogenic (fat storing) gene expression of several different enzymes involved storing fat. These enzymes include sterol regulatory element binding protein-1 (SREBP-1), acetyl-CoA carboxylase, and fatty acid synthase. Decreasing these lipogenic enzymes means that less fat is esterifized in the liver and less fat is stored in the body. Second, flax seed oil provides the essential fatty acids necessary to support optimal metabolism in the body. Supplementing with essential fatty acids can actually help your body loose fat, decrease cholesterol and reduce oxidative stress.
Ketosis
Ketogenesis occurs when fatty acid oxidation is increased to a point where the liver cannot metabolize the fatty acids completely. Excess acetyl-CoA (which can be created from glucose, fat or amino acid metabolism) is converted to ketones in the liver and released into the bloodstream for use by other tissues as fuel (specifically the brain). Ketones are very important during a low carb diet, because the brain cannot use fatty acids for fuel. The brain can use glucose, but when glucose is low, the brain will turn to ketones for its energy. Sesamin has been shown to increase ketone production. Increasing ketone production with Sesamin should have protein-sparing effect, because less amino acids will be needed to create ketones. The addition of flax seed oil to SesaMAX will also support ketogenesis and help you keep as much muscle as possible while dieting. This means your muscle mass will be spared while dieting and you will loose more fat!
Omega-3 Fish Fats
The western diet, primarily consisting of Omega-6's and 9's (meat and vegetable oils), is considerably low in omega-3 fish oils. Recent research shows that omega-3 fish oils strongly support fat loss and aids in general health promoting effects. The most beneficial and active fatty acids in fish oils are Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA). SesaMAX contains a potent omega-3 fish oil concentrate yielding a 50% EPA/DHA blend, effective at smaller doses. This is why SesaMAX™ is the most powerful fat burning, health promoting gel cap on the market.
REFRENCES:
1. Akimoto K., et al. 1993. Protective effects of sesamin against liver damage caused by alcohol or carbon tetrachloride in rodents. Ann Nutr Metab. ;37(4):218-24.
2. Ashakumary L., et al. 1999. Sesamin, a sesame lignan, is a potent inducer of hepatic fatty acid oxidation in the rat. Metabolism. Oct;48(10):1303-13.
3. Fukuda N, et al. 1999. Effect of dietary sesamin on metabolic fate of an exogenous linolelaidic acid in perfused rat liver. J Nutr Sci Vitaminol (Tokyo). Aug;45(4):437-48.
4. Hirose N., et al. 1991. Inhibition of cholesterol absorption and synthesis in rats by sesamin. J. Lipid Res. Vol 32, 629-638.
5. Ide T., et al. 2001. Sesamin, a sesame lignan, decreases fatty acid synthesis in rat liver accompanying the down-regulation of sterol regulatory element binding protein-1. Biochem Biophys Acta. Nov 30;1534(1):1-13.
6. Ide T., et al. 2003. Sesamin, a Sesame Lignan, as a Potent Lipid-Lowering Food Component. JARQ 37 (3), 151 - 158.
7. Ide T. 2004. Interaction of dietary fat types and sesamin on hepatic fatty acid oxidation in rats. Biochem Biophys Acta. Jun 1;1682(1-3):80-91.
8. Ogawa H, et al. 1995. Sesame lignans modulate cholesterol metabolism in the stroke-prone spontaneously hypertensive rat. Clint Exp Pharmacology Physiol Suppl. Dec;22(1):S310-2.
9. Utsunomiya T., et al. 2000. Effects of sesamin-supplemented dietary fat emulsions on the ex vivo production of lipopolysaccharide-induced prostanoids and tumor necrosis factor in rats. Am J Clin Nutr. Sep;72(3):804-8.
Supplement Facts per serving (1 softgel)
Calories 9
Calories from Fat 9
Total Fat 1g
Sesame Seed Oil 500mg
Minimum 50% Sesamin Lignan 250mg
Omega 3 Fish Oil Concentrate 500mg
EPA (Eicosapentaenoic Acid) 150mg
DHA (Docosahexaenoic Acid) 100mg
Other Ingredients: Gelatin, Glycerin, Purified Water, Titanium dioxide, FD&C Red # 40, FD&C Yellow # 6, FD&C Blue # 1
Recommended Use: As a dietary supplement, take one softgel 3 times daily with meals. Taking 2 softgels 3 times daily may provide greater benefit to those who tend to store body fat easily, or those who are consuming higher calorie diets as a way to prevent extra calories from storing as fat.
Warning: Keep out of reach of children. Always consult a physician prior to using any dietary supplement.
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Contains fish (anchovy and/or sardines, mackerel, jack mackerel)
Store In a cool, dry place. Protect from heat, light and moisture.